S. Nomura, A. Miyasaka, A. Maruyama, and N. Shimada, Spontaneous Liquid Droplet-to-Gel Transition of Citrulline Polypeptide Complexed with Nucleic Acids, ACS Biomater. Sci. Eng., 10, 1473-1480 (2024),
DOI: 10.1021/acsbiomaterials.3c01716
2023年
T. Komachi, S. Kawai, Y. Hirayama, A. Maruyama, and N. Shimada, Encapselation in cooling-induced coacervates augments DNA enzyme activity, Polym. Chem., 14, 4743-4747(2023), DOI: 10.1039/D3PY00923H
S. Takemura, N. Shimada, and A. Maruyama, Malachite green-derivatized cationic
comb-type copolymer acts as a photoresponsive artificial chaperone, J. Biomater. Sci. Polym. Ed., 34, 2426-2482(2023), DOI: 10.1080/09205063. 2023. 2265127 2023/9/1
J. Wang, H. Raito, N. Shimada, A. Maruyama, Enhancing responsiveness and
robustness of toehold-mediated DNA circuits by a cationic copolymer,Small, in press (2023),
DOI: 10.1002/smll.202304091
W. Zhang, S. Takahashi, N. Shimada, A. Maruyama, 2D-3D-convertible, pH-responsive lipid nanosheets, Small, 2301219 (2023), DOI: 10.1002/smll.202301219
S. Fan, T. Takada, A. Maruyama, M. Fujitsuka, K. Kawai, Programmed control of fluorescence blinking patterns based on electron transfer in DNA, Chem. Eur. J., 19, e202203552 (2023),
DOI: 10.1002/chem.202203552
O. Hanpanich, A. Lomaea, A. Maruyama, T. Palagac, O. Chailapakula, N. Ngamrojanavanich, Label-free detection of HPV mRNA with artificial chaperone-enhanced MNAzyme (ACEzyme)-based electrochemical sensor, Biosens. Bioelectron., 221, 114352 (2023)
DOI: 10.1016/j.bios.2022.114352
A. Lomaea, P. Preechakasedkit, O. Hanpanich, T. Ozer, C. S. Henry, A. Maruyama, E. Pasomsub, A. Phuphuakrat, S. Rengpipat, T. Vilaivan, O. Chailapakul, N. Ruecha, N. Ngamrojanavanich, Label free electrochemical DNA biosensor for COVID-19 diagnosis, Talanta, 253, 12399 (2023),
DOI: 10.1016/j.talanta.2022.123992
T. Masuda, S. Takahashi, T. Ochiai, T. Yamada, N. Shimada, A. Maruyama, Autonomous Vesicle/Sheet Transformation of Cell-Sized Lipid Bilayers by Hetero-Grafted Copolymers,
ACS Appl. Mater. Interfaces,,14, 53558–53566, in press (2022) DOI:10.1021/acsami.2c17435
Y. Tanaka, C. H. Niu, T. Sasaki, S. Nomura, A. Maruyama, N. Shimada, Smart
protein refolding system based on UCST-type ureido polymers,Biomacromolecules, 23, 3860–3865 (2022),
DOI: 10.1021/acs.biomac.2c00694
J. Wang, N. Shimada, and A. Maruyama, Cationic copolymer-augmented DNA hybridization chain reaction,
ACS Appl. Mater. Interfaces, 14, 39396–39403 (Aug. 2022),
DOI: 10.1021/acsami.2c11548
S. Fan, J. Xu, Y. Osakada, K. Hashimoto, K. Takayama, A. Natsume, M. Hirano, A. Maruyama,
M. Fujitsuka, K. Kawai, K. Kawai, Electron transfer kinetics through nucleic acids untangled by single-molecular fluorescence blinking,
Chem, in press (2022), DOI: 10.1016/j.chempr.2022.07.025
O. Hanpanicha, A. Lomaea, A. Maruyamab, T. Palagac, O. Chailapakula, N. Ngamrojanavanich, Label-free detection of HPV mRNA with artificial chaperone-enhanced MNAzyme (ACEzyme)-based electrochemical sensor,
Biosens. Bioelectron., in press (2022) DOI: 10.1016/j.bios.2022.114352
A. Kojima, J. Nakao, N. Shimada, N. Yoshida, Y. Abe, Y. Mikame, T. Yamamoto, T. Wada,
A. Maruyama, A. Yamayoshi, Selective photo-cross-linking detection of methylated cytosine in DNA duplex aided by a cationic comb-type copolymer,
ACS Biomater. Sci. Eng.,8, 1799-1805 (2022)
DOI: /10.1021/acsbiomaterials.2c00048
2021年
N. Yoshida, O. Hanpanichi, R. Hayashi, N. Shima, A. Maruyama, Simple and rapid RNA detection using cationic copolymer-chaperoned MNAzyme (ACEzyme),
Translat Regulat Sci. , 9,6142-6152 (2021) DOI: 10.1002/anie.202101606
Araki, H., Hagiwara, S., Shinomiya, R., Momotake, A., Kotani, H., Kojima, T., Ochiai, T., Shimada, N., Maruyama, A., and Yamamoto, Y. A cationic copolymer as a cocatalyst for a peroxidase-mimicking heme-DNAzymeBiomaterials Science 9,6142-6152 (2021) DOI: 10.1002/anie.202101606
Y. Hu, L. Lin, Z. Guo, J. Chen, A. Maruyama, H. Tian, X. Chen, In situ vaccination and gene-mediated PD-L1 blockade for enhanced tumor immunotherapy, Chinese Chemical Letter, (2021) DOI: 10.1016/j.cclet.2020.12.055
Z. Feia, Q. Fanac, H. Daia, X. Zhoua, J. Xua, Q. Maa, A. Maruyama, C. Wang, Physiologically triggered injectable red blood cell-based gel for tumor photoablation and enhanced cancer immunotherapy, Biomaterials 271, 120724 (2021). DOI: 10.1016/j.biomaterials.2021.120724
J. Xu, S. Fan, L. Xu, A. Maruyama, M. Fujitsuka, K. Kawai, Control of triplet blinking using cyclooctatetraene to access the dynamics of biomolecules at the single-molecule level,Angew. Chem. Int. Ed.(2021) DOI: 10.1002/anie.202101606
N. Ikeuchi† T. Komachi, K. Murayama, H. Asanuma, A. Maruyama, N. Shimada, Light-regulated liquid-liquid phase separation for spatiotemporal protein recruitment and cell aggregation, ACS Appl. Mater. Interfaces,13, 5652-5659 (2021) . DOI: 10.1021/acsami.0c22314
S. Kato, S. Furukawa, D. Aoki, R. Goseki, K. Oikawa, K. Tsuchiya, N. Shimada, A. Maruyama, K. Numata, H. Otsuka*, Crystallization-induced mechanofluorescence for visualization of polymer crystallization, Nat. Commun., 12, 126 (2021) . DOI: 10.1038/s41467-020-20366-y
T. Komachi, A. Maruyama*, N. Shimada*, Evaluation of cooling-induced liquid-liquid phase separation of ureido polymers as a cold-shock stress granules model, Macromolecular Biosci., 21, 2000345 (2021). DOI: 10.1002/mabi.202000345 10.1002/mabi.202000345
T. Takenaka, W. Sakamoto, S. Takahashi, N. Shimada, A. Maruyama*, Spatially regulated activation of membrane fusogenic peptides with chaperone-like ionic copolymers, J. Controlled Rel., 330, 463-469 (2021). DOI: 10.1016/j.jconrel.2020.12.030
Kiyohiko Kawai*, Mamoru Fujitsuka, Atsushi Maruyama, Single-molecule study of redox reaction kinetics by observing the fluorescence blinking, Acc. Chem. Res.,54, 1001-1010 (2021) DOI: 10.1021/acs.accounts.0c00754
2020年
Q. Fan, Q. Ma, J. Bai, J. Xu, Z. Fei, Z. Dong, A. Maruyama, K. W. Leong, Z. Liu, C. Wang, An implantable blood clot–based immune niche for enhanced cancer vaccination,
Science. Advances,
6, eabb4639 (2020) DOI: 10.1126/sciadv.abb4639
O. Hanpanich, K. Saito, N. Shimada, A. Maruyama*, One-step isothermal RNA detection with LNA-modified MNAzymes chaperoned by cationic copolymer,
Biosens. Bioelectron., 165, 112383 (2020) DOI: /10.1016/j.bios.2020.112383
K. Rudeejaroonrung, O. Hanpanich, K. Saito, N. Shimada, A. Maruyama*, Cationic copolymer enhances 8-17 DNAzyme and MNAzyme activities,
Biomater. Sci.,
8, 3812-3818 (2020) DOI: 10.1039/D0BM00428F
Y. Hu, L. Lin, J. Chen, A. Maruyama, H. Tian*, X Chen*, Synergistic tumor immunological strategy by combining tumor nanovaccine with gene-mediated extracellular matrix scavenger,
Biomaterials, 252, 120114 (2020) DOI: 10.1016/j.biomaterials.2020.120114
S. Fujii, S. Kuroyanagi, N. Shimada, J. Matsumo, J. H. Lee, R. Takahashi, A Maruyama*, K. Sakurai*, Bundling process of citrulline polypeptides upon UCST-type phase separation,
J. Phy. Chem. B, 124, 4036-4043 (2020) DOI: 10.1021/acs.jpcb.0c00934
O. Hanpanich, H. Miyaguchi, H. He, N. Shimada, A. Maruyama*, Cationic copolymer-chaperoned short armed-10-23 DNAzymes,
Nucleosides Nucleotides Nucleic Acids, 39, 156-169 (2020) DOI: 10.1080/15257770.2019.1675168
丸山厚、イオン性高分子による生体分子機能強化-第20回日本DDS学会永井賞によせて、
Drug Delivery System, 35, 410-416 (2020)
Orakan Hanpanich, Atsushi Maruyama*, Artificial chaperones, From material design to applications,
Biomaterials, Volume 254, 120150 (2020). DOI:/10.1016/j.biomaterials.2020.120150
Kiyohiko Kawai*, Atsushi Maruyama, Kinetics of Photo−Induced Reactions at the Single−Molecule Level: The KACB Method,
Chemistry, A European Journal, 23, 7740-7746 (2020) DOI: 10.1002/chem.202000439
O. Hanpanich, A. Maruyama, Cationic comb-type copolymer as an artificial chaperone Polym J 51 935-943 (2019)
O. Hanpanich, T. Oyanagi, N. Shimada, A. Maruyama, Cationic copolymer-chaperoned DNAzyme sensor for microRNA detection Biomaterials 225 119535 (2019) Osumi Journal award recorded
O. Hanpanich, A. Maruyama, Cationic comb-type copolymer as an artificial chaperone, Polym. J. 51 935-943 (2019)
N. Shimada, H. Kinoshita, T. Umegae, S. Azumai, N. Kume, T. Ochiai, T. Takenaka, W. Sakamoto, T. Yamada, T. Furuta, T. Masuda, M. Sakurai, H. Higuchi, A. Maruyama, Cationic Copolymer‐Chaperoned 2D-3D Reversible Conversion of Lipid Membranes Adv.Mater. 31 1904032 (2019)
M. Ohshio, K. Ishihara, A. Maruyama, N. Shimada, S. Yusa, Upper critical solution temperature (UCST)-type thermoresponsive nanogelLangmuir 35, 7261-7267 (2019)
T. Masuda, N. Shimada, A. Maruyama, Liposome-Surface-Initiated ARGET ATRP: Surface Softness Generated by "Grafting from" Polymerization. Langmuir 35 5581-5586 (2019)
W. Sakamoto, T. Masuda, T. Ochiai, N. Shimada, A. Maruyama, Cationic Copolymers Act As Chaperones of a Membrane-Active Peptide: Influence on Membrane Selectivity. ACS Biomaterials Science & Engineering 5 11 5744-5751 (2019)
S. Kuroyanagi, N. Shimada, S. Fujii, T. Furuta, A. Harada, K. Sakurai, A. Maruyama, Highly Ordered Polypeptide with UCST Phase Separation Behavior. J. Am. Chem. Soc.141 1261-1268 (2019) Osumi Journal award recorded
B. Cheng, H. Kashida, N. Shimada, A. Maruyama, H. Asanuma, Photo-regulatable DNA isothermal amplification by template-mediated ligation. Chem. Commun. 55 1080-1083 (2019)
X. Guan, L. Lin, J. Chen, P. Sun, Y. Hu, H. Tian, A. Maruyama, X. Chen*, Efficient PD-L1 gene silence promoted by hyaluronidase for highly enhanced cancer immunotherapyJ. Controlled Rel. 293 104-112 (2019)
T. Miyata, N. Shimada, A. Maruyama, K. Kawai, Fluorescence Redox Blinking Adaptable to Structural Analysis of Nucleic Acids. Chem. Eur-J. 24 6755-6761 (2018)
N. Shimada, T. Sasaki, T. Kawano, A. Maruyama, Rational Design of UCST-type Ureido Copolymers Based on a Hydrophobic Parameter. Biomacromolecules 19 4133-4138 (2018)
T. Masuda, N. Shimada, A. Maruyama, A Thermoresponsive Cationic Comb-Type Copolymer Enhances Membrane Disruption Activity of an Amphiphilic Peptide. Biomacromolecules 19 1333-1339 (2018)
N. Shimada, K. Saito, T. Miyata, H. Sato, S. Kobayashi, A. Maruyama, DNA Computing Boosted by a Cationic Copolymer. Adv. Funct. Mater. 28 1707406 (2018)
Y. Zhang, L. Liu, L. Lin, J. Chen, H. Tian, X. Chen, A. Maruyama, In situ Dual-crosslinked nanoparticles for tumor targeting gene delivery. Acta Biomaterialia.65 349-362 (2018)
H. Sato, N. Shimada, T. Masuda, A. Maruyama, Allosteric Control of Peroxidase-Mimicking DNAzyme Activity with Cationic Copolymers. Biomacromolecules 19 2082-2088 (2018)
2017年
K. Kawai, T. Miyata, N. Shimada, S. Ito, H. Miyasaka, A. Maruyama, Single molecule monitoring of structural switching dynamics of nucleic acids by controlling fluorescence blinking. Angew. Chem. Int. Ed.56, 15329.(2017)
A. Maruyama, N. Shimada, Cationic copolymers for DNA nanobiotechnology, Synthesis and Characterization of Biorelated Polymers for Biomedical Applications, C. Scholz Ed. Wiley & Sons, Inc.. pp. 297-312 (2017)
H. Sato, N. Shimada, A. Maruyama,Cationic Comb-Type Copolymer Promotes DNA Assembly on Gold Nanoparticles While Enhancing Particle Dispersibility . Macromol. Res. 25, 500-503 (2017)
B. Cheng, H. Kashida, N. Shimada, A. Maruyama, and H. Asanuma, Chaperone-Polymer-Assisted, Photodriven DNA Strand Displacement. ChemBioChem.18, 1568-1572 (2017)
T. Masuda, N. Shimada, T. Sasaki, A. Maruyama, A. M. Akimoto, and R. Yoshida, , Design of a Tunable Self-Oscillating Polymer with Ureido and Ru(bpy)3 Moieties. Angew. Chem. Int. Ed.. 56, 9459-9462 (2017)
W. Sakamoto, T. Ochiai, N. Shimada and A. Maruyama, Cationic copolymer augments membrane permeabilizing activity of an amphiphilic peptide J BIOMAT SCI-POLYM E.28, 1097-1108 (2017)
A. Yamayoshi, D. Miyoshi,Y. Zouzumi, Y. Matsuyama, J. Ariyoshi, N. Shimada, A. Murakami,T. Wada, A. Maruyama,Selective and Robust Stabilization of Triplex DNA Structures using Cationic Comb-type Copolymers J. Phys. Chem. B. 121, 4015-4022 (2017)
2016年
N. Shimada, M. Saito, S. Shukuri, S. Kuroyanagi, T. Kuboki, S. Kidoaki, T. Nagai, and A. Maruyama, Reversible Monolayer/Spheroid Cell Culture Switching by UCST-Type Thermoresponsive Ureido Polymers, ACS Appl. Mater. Inter. 8, 31524-31529 (2016)
Y. Ueda, A. Maruyama, S. Nakano, N. Sugimoto, D. Miyoshi, Effects of TMAO and urea on DNA duplex and G-quadruplex, Sci. & Tech. Adv. Mater. 17, 753-759.(2016)
K. Saito, N. Shimada, A. Maruyama, Cooperative enhancement of deoxyribozyme activity by chemical modification and added cationic copolymer, Sci. Tech. Adv. Mater. 17,437-442.(2016)
A. Fujihara, K. Itsuki, N. Shimada, A. Maruyama, N. Sagawa, T. Shikata, S. Yusa Preparation of Ureido Group Bearing Polymers and Their Upper Critical Solution Temperature in Water, J. Polym. Sci., Polym. Chem. 54, 2845-2854 (2016)
N. Yamaguchi, Y. Zouzumi, N. Shimada, S. Nakano, N. Sugimoto, A. Maruyama, D. Miyoshi, A reversible B?A transition of DNA duplexes induced by synthetic cationic copolymers, Chem. Commun., 52, 7446-7449 (2016)
Q. Liu, M, Somiya, N. Shimad, W. Sakamoto, N. Yoshimoto, M. Iijima, K. Tatematsu, T. Nakai, T. Okajima, A. Maruyama, S. Kuroda, Mutational analysis of hepatitis B virus pre-S1 (9?24) fusogenic peptide, Biochem. Biophys. Res. Commun., 474, 406-412 (2016)
2015年
K. Kawai, K. Higashiguchi, A. Maruyama, T. Majima, DNA microenvironment monitored by controlling redox blinking, ChemPhysChem (2015)
H. Lee, Y. Hoshino, Y. Wada, Y. Arata, A. Maruyama, Y. Miura, Minimization of synthetic polymer ligands for specific recognition and neutralization of a toxic peptide, J. Am. Chem. Soc. 137, 10878-10881 (2015)
N. Shimada, H. Kinoshita, S. Tokunaga, T. Umegae, N. Kume, W. Sakamoto, A. Maruyama, Inter-polyelectrolyte nano-assembly induces folding and activation of functional peptides, J. Controlled Release, 218, 45-52 (2015)
A. Fujihara, N. Shimada, A. Maruyama, K. Ishihara, K. Nakaia, S. Yusa, Preparation of upper critical solution temperature(UCST) responsive diblock copolymers bearing pendant ureido groups and their micelle formation behavior in water, Soft Matter, 11, 5204-5213 (2015)
J. Gao, N. Shimada, A. Maruyama, MNAzyme-catalysed nucleic acid detection enhanced by a cationic copolymer, Biomater. Sci., 3, 716-720 (2015)
K. Kawai, A. Maruyama, Triple helix conformation-specific blinking of Cy3 in DNA, Chem. Commun., 51, 4861-4864 (2015)
J. Gao, N. Shimada, A. Maruyama, Enhancement of deoxyribozyme activity by cationic copolymers, Biomater. Sci., 3, 308-316 (2015)
2014年
N. Shimada, S. Kidoaki, A. Maruyama, Smart hydrogels exhibiting UCST-type volume changes under physiologically relevant conditions, RSC Advances, 4, 52346-52348 (2014)
D. Miyoshi, Y. M. Ueda, N. Shimada, S. I. Nakano, N. Sugimoto, A. Maruyama, Drastic stabilization of parallel DNA hybridizations by a polylysine omb-type copolymer with hydrophilic graft chain, ChemMedChem., 9, 2156-63 (2014)
S. Yusa, M. Morihara, K. Nakai, S. Fujii, Y. Nakamura, A. Maruyama, N. Shimada, Thermo-responsive liquid marbles, Polym. J. 2013
K. Kawai, T. Koshino, A. Maruyama, T. Majima, Blinking Triggered by The change in the solvent accessibility of a fluorescent molecule, Chem. Commun., 50, 10478-81 (2014)
R. Arivazhagan, M.Endo, K. Hidaka, N. Shimada, A. Maruyama, H. Sugiyama, Lock-and-key mechanism for the controllable fabrication of DNA origami structures, Chem. Commun., 50, 8743-6 (2014)
A. Maruyama, N. Sonda, K. Yamasaki, M. Hirano, S. Kidoaki, N. Shimada, M. Maeshiro, M. Miyazaki, Cationic Comb-Type Copolymer Excludes Intercalating Dye from DNA Without Inducing DNA Condensation. Current Nanoscience 2014 Volume 10, 185-188 (2014)
N. Shimada, W. Song, and A. Maruyama, DNA Strand Exchange Reaction activated by Cationic Comb-type Copolymer Having Ureido Groups, Biomater. Sci. 2, 1480-1485 (2014)
2013年
J. Chen, H. Tian, X. Dong, Z. Guo, Z. Jiao, F. Li, A. Kano, A. Maruyama, X. Chen, Effective tumor treatment by VEGF siRNA complexed with hydrophobic poly(amino acid)-modified polyethylenimine, Macromol. Biosci., 13, 1438-46 (2013)
H. Saneyoshi, N. Shimada, A. Maruyama, Y. Ito, H. Abe, Bioorg Med Chem Lett. 23 (2013) 6851-6853.
N. Shimada, A. Maruyama, Thermoresponsive Polymers with Functional Groups
Selected for Pharmaceutical and Biomedical Applications. 2013, 1135, 235-241.
A. Maruyama, N. Sonda, K. Yamasaki, S. Kidoaki, N. Shimada, M. Maeshiro,
M. Miyazaki, Cationic comb-type copolymer excludes intercalating dye from
DNA without inducing DNA condensation, Curr. Nanosci., Accepted.
A. Maruyama, N. Makita, S. W. Choi, S. Inoue, C. Lesoil, A. Yamayoshi,
N. Shimada, A. Kano, T. Akaike, DNA Nanomachine chaperoned by cationic
copolymers, Mater. Chem. Phys., accepted.
K. Kawai, T. Majima, A. Maruyama, Detection of Single-Nucleotide Variations by Monitoring the Blinking of Fluorescence Induced by Charge Transfer in DNA, ChemBioChem., 14, 1430-1433, 2013
N. Shimada, M. Nakayama, A. Kano, A. Maruyama,Design of UCST Polymers
for Chilling Capture of Proteins. , Biomacromolecules, 2013, 14 (5), 1452-1457
J. Du, L. Wu, N. Shimada, A. Kano, A. Maruyama, Polyelectrolyte-Assisted
Transconformation of Stem-loop DNA, Chem. Commun., 49, 475-477 (2013)
Arihiro Kano, Yuki Taniwaki, Izumi Nakamura, Naohiko Shimada, Kenji
Moriyama, Atsushi Maruyama,Tumor delivery of PhotofrinR by PLL-g-PEG
for photodynamic therapy.Journal of Controlled Release. , 2013, 167(3)
315-321
M. Nishihara, K. Imato, A. Irie, T. Kanehara, A. Kano, A. Maruyama, A.
Takahara, H. Otsuka, Reversibly Cross-linked Polymeric Micelles Formed
by Autonomously Exchangeable Dynamic Covalent Bonds, Chem. Lett.,42, 377-379 (2013)
J. Michaelis, A. Maruyama, O. Seitz, Promoting strand exchange in a DNA
templated transfer reaction, Chem. Commun., 49, 618-620 (2013)
2012年
A. Shimoda, S. Sawada, A. Kano, A. Maruyama, A. Moquin, F. M. Winnik, K.
Akiyoshi, Dual crosslinked hydrogel nanoparticles by nanogel bottom-up
method for sustained-release delivery, Col. Surf., B: Biointerfaces, 99,
38-44 (2012)
T. Wada, A. Kano, N. Shimada, A. Maruyama, α-Amino acid pendant polymers
as endosomal pH-responsive gene carriers, Macromol. Res., 20, 302-308 (2012)
H. Asanuma, T. Osawa, H. Kashida, T. Fujii, X. Liang, K. Niwa, Y.Yoshida,
N. Shimada, A. Maruyama, A polycation-chaperoned in-stem molecular beacon
system, Chem. Commun., 48, 1760 ? 1762, (2012)
Kano, A., Moriyama, K., Yamano, T., Nakamura, I., Shimada, N., and Maruyama,
A., Grafting of poly(ethylene glycol) to poly-lysine augments its lifetime
in blood circulation and accumulation in tumors without loss of the ability
to associate with siRNA. J Control Release, 149, 2-7 (2011)
R. Moriyama, N. Shimada, A. Kano, A. Maruyama, DNA assembly and re-assembly
activated by cationic comb-type copolymer. Biomaterials, 32(9), 2351-2358
(2011)
T. Ishihara, A. Kano, K. Obara, M. Saito, X. Chen, T. G. Park, T. Akaike
and A. Maruyama, Nuclear localization and antisense effect of PNA internalized
by ASGP-R-mediated endocytosis with protein/DNA conjugates. J Control Release,
155, 34-39 (2011)
N. Sonda, M. Hirano, N. Shimada, A. Kano, S. Kidoaki and A. Maruyama, Cationic
Comb-type Copolymers Do Not Cause Collapse but Shrinkage of DNA Molecules.
Chemistry Letters, 40, 250-251 (2011)
R. Moriyama, N. Shimada, A. Kano, A. Maruyama, The Role of Cationic Comb-type
Copolymers in Chaperoning DNA Annealing. Biomaterials, 32, 7671-7676 (2011)
N. Shimada, H. Ino, K. Maie, M. Nakayama, A. Kano, A. Maruyama, Ureido-Derivatized
Polymers Based on Both Poly(allylurea) and Poly(L-citrulline) Exhibit UCST-Type
Phase Transition Behavior under Physiologically Relevant Conditions. Biomacromolecules,
10(12), 3418-3422 (2011)
P. L. T. Tran, R. Moriyama, A. Maruyama, B. Rayner and J. L. Mergny, A
mirror-image tetramolecular DNA quadruplex. Chem. Comm., 47(19), 5437-5439
(2011)
Moriyama R., Mochida J., Yamayoshi A., Shimada N., Kano A., Maruyama A,
Preparation of Cationic Comb-Type Copolymer Having Tetra-Alkylammonium
Groups and its Interaction with DNA. Curr Nanosci., 7, 979-983 (2011).
2010年
M. R. Berber, H. Mori, I. H. Hafez, K. Minagawa, M. Tanaka, T. Niidome,
Y. Katayama, A. Maruyama, T. Hirano, Y. Maeda and T. Mori, Unusually Large
Hysteresis of Temperature-Responsive Poly(N-ethyl-2-propionamidoacrylamide)
Studied by Microcalorimetry and FT-IR. J. Phys. Chem. B, 114(23), 7784-7790
(2010)
Shimada, N., Yamamoto, M., Kano, A., and Maruyama, A., Cationic Graft Copolymer
as a DNA B-Z Transition Inducer: Effect of Copolymer Structure. Biomacromolecules,
11, 11, 3043-3048 (2010)
S. Mochizuki, A. Kano, N. Shimada, A. Maruyama, Uptake of enzymatically-digested
hyaluronan by endothelial liver cells in vivo and in vitro. J. Biomater.
Sci. Polymer Edn., 20, 83-97 (2009)
H. Torigoe, A. Maruyama, S. Obika, T. Imanishi, and T. Katayama, Synergistic
Stabilization of Nucleic Acid Assembly by 2'-O,4'-C-Methylene-Bridged Nucleic
Acid Modification and Additions of Comb-Type Cationic Copolymers. Biochemistry,
48, 3545-3553 (2009)
N. Shimada, A. Kano and A. Maruyama, B?Z DNA Transition Triggered by a
Cationic Comb-Type Copolymer. Advanced Functional Materials, 19(22), 3590-3595
(2009)
Morimoto, N., Tamada, J., Sawada, S., Shimada, N., Kano, A., Maruyama,
A., and Akiyoshi, K., Interaction of Self-assembled Cationic Nanogels with
Oligo-DNA and Function as Artificial Nucleic Acid Chaperone. Chemistry
Letters, 38(5), 496-497 (2009)
Chen, J., Tian, H., Guo, Z., Xia, J., Kano, A., Maruyama, A., Jing, X.,
and Chen, X., A highly efficient siRNA carrier of PBLG modified hyperbranched
PEI. Macromol Biosci., 9(12), 1247-53 (2009)
Moriyama, R., Shimada, N., Kano, A., and Maruyama, A., Cationic comb-type
copolymer as a nucleic acid chaperone for DNA quadruplex. Nucleic Acids
Symp Ser., 53, 61-2 (2009)
Reddy, T.T., Kano, A., Maruyama, A., Hadano, M., and Takahara, A., Synthesis
and characterization of semi-interpenetrating polymer networks based on
polyurethane and N-isopropylacrylamide for wound dressing. J Biomed Mater
Res B Appl Biomater., 88(1), 32-40 (2009)
Shimada, N., Kano, A., and Maruyama, A., Design of cationic graft copolymers
as a potential inducer of B-Z transition. Nucleic Acids Symp Ser., 53,
251-2 (2009)
Shimada, N., Kano, A., and Maruyama, A., B-Z DNA Transition Triggered by
a Cationic Comb-Type Copolymer. Advanced Functional Materials. Advanced
Functional Materials, 19(22), 3590-3595 (2009)
Thatiparti, T.R., Kano, A., Maruyama, A., and Takahara, A., Novel Silver-Loaded
Semi-Interpenetrating Polymer Network Gel Films with Antibacterial Activity.
Journal of Polymer Science Part a-Polymer Chemistry, 47(19), 4950-4962
(2009)
2008年
S. W. Choi, A. Kano and A. Maruyama, Activation of DNA strand exchange
by cationic comb-type copolymers: effect of cationic moieties of the copolymers.
Nucleic Acids Res., 36(1), 342-51 (2008)
H. Q. Zhang, S. Haga, M. Fukai, Y. Oikawa, H. Inoue, W. Ogawa, A. Kano,
A. Maruyama, X. Y. Fu, S. Todo, S. Enosawa and M. Ozaki, Identification
of de novo STAT3 target gene in liver regeneration. Hepatol Res., 38(4),
374-384 (2008)
T. T. Reddy, A. Kano, A. Maruyama, M. Hadano and A. Takahara, Thermosensitive
transparent semi-interpenetrating polymer networks for wound dressing and
cell adhesion control. Biomacromolecules, 9(4), 1313-1321 (2008)
A. Kano, T. Yamano, S. W. Choi, A. Maruyama, Polymer brush-stabilized polyplex for a siRNA carrier with long blood circulatory half-life. Advanced Materials Research. 47-50, 762-764 (2008)
A. Maruyama, L. Wu, N. Shimada and A. Kano, Kinetic Effect of Cationic
Comb-type Copolymers on DNA Hybridization, Advanced Materials Research,
47-50, 1355-1358 (2008)
2007年
Makita, N., Choi, S. W., Kano, A., Yamayoshi, A., Akaike, T., Maruyama,
A., Effect of cationic copolymer on quadruplex folding of human telomeric
DNA, Nucleosides, Nucleotides Nucleic Acids, 26, 1115-1119 (2007).
Choi, S. W., Makita, N., Kano, A., Yamayoshi, A., Akaike, T., Maruyama, A., DNA nanomachine switching
improved by cationic comb-type copolymer. Macromol. Symp., 249-250, 317-321
(2007).
Choi, S. W., Yamayoshi, A., Hirai, M., Yamano, T., Takagi, M., Sato, A.,
Kano A., Shimamoto, A., Maruyama, A., Preparation of cationic comb-type
copolymers having high density of peg graft chains for gene carriers. Macromol.
Symp., 249-250, 312-316 (2007).
Choi, S. W., Makita, N., Inoue, S., Lesoil, C., Yamayoshi, A., Kano, A., Akaike, T., Maruyama, A., Cationic comb-type copolymers for boosting
DNA-fueled nanomachines. Nano Lett., 7, 172-178 (2007).
K. Yamana, Y. Ohshita,Y. Fukunaga, M. Nakamura, A. Maruyama, Bis-Pyrene-Labeled
Molecular Beacon: A Monomer-Excimer Switching Probe for the Detection of
DNA Base Alteration, Bioorganic & Medicinal Chemistry. (accepted).
Sato, Y., Moriyama R., Choi, S. W., Kano, A., Maruyama, A. Spectroscopic investigation of cationic comb-type copolymers/DNA
interaction: interpolyelectrolyte complex enhancement synchronized with
DNA hybridization. Langmuir, 23, 65-69 (2007).
2006年
T. Ooya, H. S. Choi, A. Yamashita, N. Yui, Y. Sugaya, A. Kano, A. Maruyama, H. Akita, K. Kogure, H. Harashima, Biocleavable polyrotaxane-plasmid DNA polyplex for enhanced gene delivery, J. Am. Chem. Soc., 128, 3852-3853 (2006).
S. Mochizuki, A. Kano, A. Yamayoshi, A. Maruyama, Hyaluronan conjugation
of antigenic protein to modify immunogenic information. Science and Technology
of Advanced Materials, 7 (7), 685-691(2006).
E. H. Chowdhury, A. Maruyama, A. Kano, M. Nagaoka, M. Kotaka, S. Hirose,
M. Kuno, T. Akaike, pH-sensing nano-crystals of carbonate apatite: Effects
on intracellular deliverty and release of DNA for efficient expression
into mammalian cells, Gene, 87-94 (2006).
D. Ishii, K. Muraki, A. Kano, A. Yamayoshi, A. Maruyama, Single-base mismatch recognition using partially double-stranded probe having various length, Nucleic Acids. Symp. Ser., 50, 325-326 (2006).
Takada, K., Choi, S. W., Yamayoshi, A., Kano, A., Maruyama, A., Structural effect of cationic copolymers on nucleic
acid-chaperoning activity. Nucleic Acids Symp. Ser., 50, 27-28 (2006).
H. Torigoe, T. Katayama, S. Obika, A. Maruayma, T. Imanishi, Combination
of poly(L-lysine)-graft-dextran copolymer and 2’-O, 4’-C-methylene bridged
nucleic acid (2’, 4’-BNA) modification synergistically stabilizes pyrimidine
motif triplex at neutral pH, Nucleosides, Nucleotides, and Nucleic Acids,
24, 635-638 (2005)
R. Ushijima, N. Sakaguchi, A. Kano, A. Maruyama, Y. Miyamoto, T. Sekimoto, Y. Yoneda, K. Ogino, T. Tachibana, Extracellular signal-dependent nuclear import of STAT3 is mediated by various importin alphas, Biochem. Biophys. Res. Comm., 330, 880-886 (2005).
H. Torigoe, A. Maruyama, Synergistic stabilization of nucleic acid assembly
by oligo-N3’->P5’ phosphoramidate modification and comb-type cationic
copolymer, J. Amer. Chem. Soc., 127, 1705-1710 (2005)
Y. Sato, Y. Kobayashi, T. Kamiya, H. Watanabe, T. Akaike, K. Yoshikawa,
A. Maruyama, The effect of backbone structure on polycation comb-type copolymer/DNA
interactions and the molecular assembly, Biomaterials, 26(7), 703-11 (2005).
Choi, S. W., Takada, K., Mochida, J., Yamayoshi, A., Kano, A., Maruyama, A., The molecular structure effect of cationic comb-type copolymers on nucleic acid chaperone activity. Nucleic Acids Symp. Ser., 49, 329-330 (2005).
Takei, Yoshiyuki; Ikejima, Kenichi; Enomoto, Nobuyuki; Maruyama, Atsushi; Sato, Nobuhiro.Genetic manipulation of liver sinusoidal endothelial cells, Keio University
International Symposia for Life Sciences and Medicine, 13(Organ Microcirculation),
129-134(2005).
K. Yamana,Y. Fukunaga,Y. Ohtania,S. Sato,M. Nakamura,W. J. Kim,T. Akaike, A. Maruyama, DNA mismatch detection using a pyrene? excimer-forming probe, Chem. Commun.,
19, 2509-2511 (2005)
Sung Won Choi, Yuichi Sato, Toshihiro Akaike, Atsushi Maruyama, Preparation of cationic comb-type copolymer having guanidino moieties and its interaction with DNAs, J. Biomater. Sci. Polymer Edn, 15(9), 1099-110 (2004)
Ooya Tooru, Yamashita Atsushi, Kurisawa Motoichi, Sugaya Yuko, Maruyama Atsushi, Yui Nobuhiko, Effects of polyrotaxane structure on polyion complexation with DNA, Science and Technology of Advanced Materials, 5, 363-369 (2004)
A. Maruyama, Nucleic acid chaperone-inspired materials, Biomaterials-based
delivery and biocompatibility of proteins and nucleic acids, Ed. R. I.
Mahato, CRC Press, pp. 601-614 (2004)
S. W. Choi,Y. Sato,T. Akaike,A. Maruyama, Evaluation of comb-type copolymers with different cationic groups as artificial nucleic acid chaperones, Nucleic Acids Sym. Ser., No. 48, 273-274 (2004)
K. Hirata, Y. Sato, A. Kano, T. Akaike, A. Maruyama, Nucleation-synchronized strand displacement for highly sensitive DNA analysis,Nucleic Acids Sym. Ser., No. 48, 267-268 (2004)
T. Katayama, A. Maruyama, S. Obika, T. Imanishi, H, Torigoe, Synergistic stabilization of triplex by combination of comb-type cationic copolymer and 2',4'-BNA, Nucleic Acids Sym. Ser., No. 48, 139-140 (2004)
N. Makita, S. Inoue, T. Akaike, A. Maruyama, Improved performance of a DNA nanomachine by cationic copolymers, Nucleic Acids Sym. Ser., No. 48, 173-174, (2004)
W. J. Kim, Yuichi Sato, Toshihiro Akaike, Atsushi Maruyama, Cationic comb-type copolymers for DNA analysis, Nature materials, 2, 815-820 (2003)
Kim Won Jong, Sato Yuichi, Akaike Toshihiro, Maruyama Atsushi, Polycation-accelerated
strand exchange (PASE) for SNPs typing, Nucleic Acids Research Supplement
(2003)
K. Tajima, W. J. Kim, Y. Sato, T. Akaike, A. Maruyama, Simple basic peptides
activate DNA strand exchange, Chem. Lett. 32, 470-471 (2003)
Torigoe Hidetaka, Akaike Toshihiro, Maruyama Atsushi, Rational combination
of strategies to achieve synergistic stabilization of triplex, Nucleic
Acids Research Supplement (2003)
Maruyama Atsushi, Inoue Satoru, Tajima Kaori, Sato Yuichi, Kim Won Jong,
Akaike Toshihiro, Design of artificial nucleic acid chaperones for DNA
engineering, Nucleic Acids Research Supplement (2003)
Sato Yuichi, Kim Won Jon, Saito Minako, Kano Arihiro, Akaike Toshihiro,
Maruyama Atsushi, Cationic comb-type copolymers as an artificial nucleic
acid chaperone: Spectroscopic analyses for DNA/copolymer interaction, Nucleic
Acids Research Supplement (2003)
W. J. Kim, T. Akaike, A. Maruyama, DNA strand exchange stimulated by spontaneous
complex formation with cationic comb-type copolymer, J. Am. Chem. Soc.,
124, 12676-12677 (2002).
Y. Sato, W. J. Kim, S. W. Choi, M. Saito, A. Kano, T. Akaike, A. Maruyama,
Investigation of DNA strand exchange mechanisms mediated by cationic polymers,
Nucleic Acids Res. Suppl., No. 2, 59-60 (2002).
K. Tajima, W. J. Kim, T. Akaike, A. Maruyama, Acceleration of DNA strand
exchange reaction by cationic polymers, Nucleic Acids Res. Suppl., No.
2, 265-266 (2002).
M. Mikawa, T. Yokawa, N. Miwa, B. Brautigam, T. Akaike, A. Maruyama, An
intelligent MRI contrast agent for tumor sensing, Academic Radiology, supple.,
(2002) in press
H. Akashi, H. Kawasaki, W. J. Kim, T. Akaike, K. Taira, A. Maruyama, Enhancement
in the cleavage activity of a hammerhead ribozyme by cationic comb-type
polymers and an RNA helicase in vitro, J. Biochem.,131, in press (2002)
2001年
K. Obara, T. Ishihara, T. Akaike, A. MaruyamaProtein/oligonucleotide conjugates
as a cell specific PNA carrier, Nucleic Acids Res. Suppl., No. 1, 217-218
(2001).
4. W. J. Kim, T. Akaike, A. Maruyama, Polycation graft copolymers accelerating
DNA strand exchange: involvement of ionic interaction, Nucleic Acids Res.
Suppl., No. 1, 151-152, (2001).
5. H. Torigoe, T. Akaike. A. Maruyama, Synergistic stabilization of triplex
by combination of comb-type cationic copolymer and oligo-N3'->P5' phospharamidates,
Nucleic Acids Res. Suppl., No. 1, 195-196 (2001).
S. Asayama, T. Akaike, A. Maruyama, Bi-phaseic polycation for the DNA carrier
responding to endosomal pH, Colloids Surf. B., 22, 183-191 (2001).
M. Nogawa, T. Ishihara, T. Akaike, A. Maruyama, Polyethylenimine/arabinogalactan
conjugate as a hepatocyte specific gene carrier, STP Pharma Sci., 11, 97-102
(2001).
W. J. Kim, T. Ishihara, T. Akaike, A. Maruyama, Comb-type cationic copolymer
expediates DNA strand exchange while stabilizing DNA duplex, Chem. Eur.
J., 7, 176-180 (2001).
C. S. Cho, A. Kobayashi, R. Takei, T. Ishihara, A. Maruyama, T. Akaike,
Receptor-mediated cell modulator delivery to hepatocyte using nanoparticles
coated with carbohydrate-carrying polymers, Biomaterials, 22, 45-51 (2001).
2000年
W. J. Kim, T. Ishihara, T. Akaike, A. Maruyama, Accelaration of DNA strand
exchange by polycation comb-type copolymer, Nucleic Acids Sym. Ser., 44,
289-290 (2000).
M. Ueda, M. Saito, T. Ishihara T. Akaike, A. Maruyama, Triplex formation
using ODN conjugates with polycation comb-type copolymer, Nucleic Acids
Sym. Ser., 44, 209-210 (2000).
1 K.-H. Park, M. Goto, R. Takei, A. Maruyama, K. Kobayashi, J. Miyazaki,
C.-S. Cho, T. Akaike, Enhanced effect of sulfonylurea(SU) in copolymer
comprising a sugar moiety and SU derivative as double ligands on insulin
secretion from MIN6 cells, J. Biomater. Sci. Polymer Edn, 11, 903-913 (2000).
A. Ferdous, T. Akaike, A. Maruyama, Mechanism of intermolecular purine-purine-pyrimidine
triple helix stabilization by comb-type polylysine graft copolymer at physiologic
potassium concentration, Bioconjugate Chem., 11, 520-526 (2000).
A. Ferdous, T. Akaike, A. Maruyama, Inhibition of sequence-specific protein-DNA
interaction and restriction endonuclease cleavage via triplex stabilization
by poly(L-lysine)-graft-dextran copolymer, Biomacromolecules, 1, 186-193
(2000).
M. Mikawa, N. Miwa, M. Brautigam, T. Akaike, A. Maruyama, Gd3+-loaded polyion
complex for pH depiction with magnetic resonance imaging, J. Biomed. Mater.
Res., 49, 390-395 (2000).
1999年
W. J. Kim, T. Ishihara, T. Akaike, A. Maruyama, Acceleration of DNA strand
exchange by polycation comb-type copolymer, Nucleic Acids Sym. Ser., 42,
139-140 (1999) .
A Maruyama, M. Saito, M. Ueda, H. Watanabe, T. Akaike, Preparation and
evaluation of ODN conjugates with polycation comb-type copolymer, Nucleic
Acids Sym. Ser., 42, 97-98 (1999).
H. Torigoe, T. Akaike, A. Maruyama, Promotion mechanism of triplex DNA
formation by comb-type polycations: Thermodynamic analyses of sequence
specificity and ionic strength dependence, Nucleic Acids Sym. Ser., 42,
137-138 (1999) .
Y. Takei, A. Maruyama, S. Kuwano, Y. Nishimura, S. Asayama, M. Nogawa,
K. Ikejima, M. Hori, T. Akaike, J. J. Lemasters, S. Watanabe, N. Sato,
Targeted gene transfer to sinusoidal endothelial cells and expression in
vivo, Transplant Proc., 790-791 (1999)
A. Maruyama, A. Ferdous, T. Ishihara, S. Asayama, J. U. Park, M. Nogawa,
H. Watanabe, Y. Takei, T. Akaike, Comb-type copolymers for controlled DNA
delivery, Nucleosides Nucleotides, 18, 1681-1682 (1999).
J.U.Park, T. Ishihara, A. Kano, T. Akaike, A. Maruyama, Preparation of dendritic
graft copolymer consisting of poly(L-lysine) and arabinogaractan as a hepatocyte
specific DNA carrier, Prep. Biochem. Biotech., 29, 353-370 (1999).
H. Torigoe, A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama, Poly(L-lysine)-graft-dextran
copolymer remarkably promotes pyrimidine-motif triplex formation at neutral
pH: Thermodynamic and kinetic studies, Nucleoside Nucleotides, 18, 1655-1656
(1999).
A. Maruyama, Y. Ohnishi, H. Watanabe, H. Torigoe, A. Ferdous, T. Akaike,
Polycation Comb-type copolymer reduces counterion condensation effect to
stabilize DNA duplex and triplex formation, Colloids Surf. B, 16, 273-280
(1999).
A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama, Relative effects of graft
copolymer and polyamines on triplex stabilization under physiological conditions,
Nucleoside Nucleotides, 18, 1651-1653 (1999).
S. Asayama, A. Maruyama, T. Akaike, Comb-type prepolymers consisting of
a polyacrylamide backbone and poly(L-lysine graft chains for multivalent
ligands, Bioconjugate Chem., 10, 246-253 (1999).
A. Maruyama, T. Ishihara, J. -S. Kim, S. W. Kim, T. Akaike, Design of multi-layered
nanoparticles as a DNA carrier, Colloids Surf. A, 153, 439-443 (1999).
H. Torigoe, A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama, Poly(l-lysine)-graft-dextran
copolymer promotes pyrimidine motif triplex DNA formation at physiological
pH. Thermodynamic and kinetic studies. J. Biol. Chem., 274, 6161-6167 (1999).
1998年
A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama, Comb-type copolymer: Triplex
stabilization to compete endonuclease activity, Nucleic Acids Sym. Ser.,
No. 39, 71-72 (1998).
H. Torigoe, A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama, Promotion
of pyrimidine-motif triplex formation by poly(L-lysine)-graft-dextran copolymer:
Thermodynamic and kinetic studies, Nucleic Acids Sym. Ser., No. 39, 131-132
(1998).
A. Maruyama, Y. Kobayashi, H. Watanabe, A. Ferdous, T. Akaike, Promotion
of triple helical DNA formation by comb-type polycation copolymers: Influence
of polymer structure, Nucleic Acid Sym. Ser., No. 39, 133-134 (1998).
A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama, Comb-type copolymer: Stabilization
of triplex DNA and possible application in antigene strategy, J. Pharm.
Sci., 87, 1400-1405 (1998).
A. Ferdous, H. Watanabe, T. Akaike, A. Maruyama, Poly(L-lysine)-graft-dextran
copolymer: Amazing effect on triplex stabilization under physiological
relevant conditions (in vitro), Nucleic Acids Res., 26, 3949-3954 (1998).
S. Asayama, M. Nogawa, Y. Takei, T. Akaike, A. Maruyama, Synthesis of novel
polyampholyte comb-type copolymers consisting of poly(L-lysine) backbone
and hyaluronic acid side chains for a DNA carrier, Bioconjugate Chem.,
9, 476-481 (1998).
J. -S. Kim, A. Maruyama, T. Akaike, S. W. Kim, A new non-viral DNA delivery
vector: The terplex system, J. Controlled Release, 53, 175-182 (1998).
M. Mikawa, N. Miwa, M. Brautigam, T. Akaike, A. Maruyama, A pH-sensitive
contrast agent for functional magnetic resonance imaging (MRI), Chem Lett.
No. 7, 693-694 (1998).
A. Maruyama, H. Watanabe, A. Ferdous, M. Katoh, T. Ishihara, T. Akaike,
Characterization of interpolyelectrolyte complexs between double-stranded
DNA and polylysine comb-type copolymers having hydrophilic side chains,
Bioconjugate Chem., 9, 292-299 (1998).
J. -S. Kim, A. Maruyama, T. Akaike, S. W. Kim, Terplex DNA delivery system
as a gene carrier, Pharm. Res., 15, 116-121 (1998).
1997年
A. Maruyama, H. Watanabe, A. Ferdous, T. Akaike, Poly(L-lysine)-graft-dextran copolymer is a novel stabilizer of triplex DNA(I): Stabilization of poly(dA)・2poly(dT) triplex, Nucleic Acid Sym. Ser., No. 37, 225-226 (1997).
A. Ferdous, A. Maruyama, H. Watanabe, T. Akaike, Poly(L-lysine)-graft-dextran
copolymer is a novel stabilizer of triplex DNA(II): Potassium-insensitive
triplex formation, Nucleic Acid Sym. Ser., No. 37, 301-302 (1997)
S. Asayama, A. Maruyama, C. -S. Cho, T. Akaike, Design of comb-type polyamine
copolymers for a novel pH-sensitive DNA carrier, Bioconjugate Chem., 8,
833-838 (1997).
R. Takei, K. -H. Park, H. Ise, A. Maruyama, T. Akaike, Immobilized anti-receptor
antibody as an extracellular matrix for liver tissue engineering, Tissue
Engineering, 3, 281-288 (1997).
A. Maruyama, T. Ishihara, T. Akaike, J. -S. Kim, S. W. Kim, A nanoparticle
DNA carrier with poly(L-lysine) grafted polysaccharide copolymer and poly(D,
L-lactic acid), Bioconjugate Chem., 8, 735-742 (1997).
K. -H. Park, R. Takei, M. Goto, A. Maruyama, A. Kobayashi, K. Kobayashi,
T. Akaike, Specific interaction between erythrocyte and glucose carrying
polymer mediated by type-1 glucose transporter(GLUT-1) on cell membrane,
J. Biochem., 121, 997-1001 (1997).
K. Hatanaka, H. Takeshige, A. Maruyama, J. Oishi, Y. Kajihara, H. Hashimoto,
New polymeric inhibitor of galactosyl transferase, J. Carbohydr. Chem.,
16, 667-672 (1997).
J. -S. Kim, A. Maruyama, T. Akaike, S. W. Kim, In vitro gene expression
on smooth muscle cells using a terplex delivery system, J. Contr. Rel,
47, 51-59 (1997).
A. Maruyama, M. Katoh, T. Ishihara, T. Akaike, Comb-type polycations effectively
stabilize DNA triplex, Bioconjugate Chem., 8, 3-6 (1997).
C. S. Cho, Y. I. Jeong, T. Ishihara, R. Takei, J. U. Park, K. H. Park,
A. Maruyama, T. Akaike, Simple preparation of nanoparticles coated with
carbohydrate-carrying polymers, Biomaterials, 18, 323-326 (1997)